Atopic dermatitis: staphylococci-dominated microbiome influence skin barrier function

Staphylococcus aureus is the dominat skin associated bacterium in atopic dermatis. A recently published Paper of CAI Researchers in cooperation with researchers from Zurich could show that this microbiome dysbiosis influence also the skin barrier function.



Relations between epidermal barrier dysregulation and staphylococci-dominated microbiome dysbiosis in atopic dermatitis.

Altunbulakli C, Reiger M, Neumann AU, Garzorz-Stark N, Fleming M, Huelpuesch C, Castro-Giner F, Eyerich K, Akdis CA, Traidl-Hoffmann C.

J Allergy Clin Immunol. 2018 Jul

Press release TUM, August 10, 2018 (in german language)


Sucsessful EAACI congress for CAI Members - Congratulation to all Poster Prize Winners

The Poster Proize Winners are:

  • Julia Schilling, HMGU/ZAUM "E1- and E2 epithelial cell models for allergy research"
  • Sabina Illing HMGU  "Farming, cytokines, 17q21 and wheeze in the first year of life"
  • Joana Candeias, ZAUM/HMGU  "Allergic sensitizations in 5-6 year old rural vs. urban children in Germany"
  • Manja Jargosch, ZAUM/HMGU  "Necroptosis as special type of cell death in inflammatory skin diseases IAF Helmholtz"
  • Paul Schmidle, TUM Biederstein clinic for Dermatogoly and Allergology "Recall urticaria in two young patients with alpha-gal-syndrome after tick bites"
  • Larissa Lewitan, ZAUM/HMGU "Induced sputum transcriptome reveals biomarker pattern in patients with allergic rhinitis and asthma"
  • Alexander Heldner, ZAUM/HMGU "Influence of synbiotics on the t cell response of grass pollen-allergic individuals in vitro"
  • Chari Jirmo ZAUM, ZAUM/HMGU & TUM ENT Clinic "Impaired conventional dendritic cell migration in absence of IL-17 in a model of experimental allergic asthma correlates with attenuated airway hyperresponsiveness and airway inflammation"
  • Tilo Biedermann, TUM Biederstein Clinic for Dermatology and Allergology "Potential treatment of pollen food syndrome using birch AIT - a study investigating the effect of the SQ tree SLIT-tablet on symptoms during an apple challenge"

The Pollen Indicator processes the data provided by the network of 8 robotic pollen monitors in Bavaria with just a 3hrs time lag.

Bavaria is world-wide the first state that implemented a network of pollen monitors that, by image recognition, determine the quantity of pollen in the air. This data is provided online for free. The Pollen Indicator connects to the pollen robot in Munich and displays the concentrations of different pollen currently in the air in Munich. Vertically the expected level of allergic symptoms is displayed, horizontally the exact concentration of airborne pollen is displayed.

ZAUM expects that this Pollen Indicator helps Bavarian Citizens to better cope with their allergic diseases and to create awareness, by delivering actual pollen counts.

New Allergen of insect venom discovered

CAI researcher of the TUM - Department Dermatology and Allergology and the Center of Allergy and environment (ZAUM) in cooperation with researcher from Spain, Luxembourg and Denmark recently discovered Pol d 3, a dipeptidyl peptidase, as the main allergen of the Polistes dominula venom.
The insect Polistes dominula is widespread in Southern Europe as well as in the United States but it will spread due to the climate change also to Western Europe. The discovery of Pol d 3 might form the basis for a proper diagnosis of Polistes venom allergy in the future.



Dr. Katja Landgraf-Rauf

Geschäftsstellenleitung CAI

Biedersteiner Strasse 29

80802 München

+49 89 4140 3329

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