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Publikationen 2018


Biomatrix for upper and lower airway biomarkers in patients with allergic asthma.

Zissler UM, Ulrich M, Jakwerth CA, Rothkirch S, Guerth F, Weckmann M, Schiemann M, Haller B, Schmidt-Weber CB, Chaker AM.

J Allergy Clin Immunol. 2018 Dec


Virus-like particles (VLP) in prophylaxis and immunotherapy of allergic diseases.

Klimek L, Kündig T, Kramer MF, Guethoff S, Jensen-Jarolim E, Schmidt-Weber CB, Palomares O, Mohsen MO, Jakob T, Bachmann M.

Allergo J Int. 2018 - Review.


Early IL-10 producing B-cells and coinciding Th/Tr17 shifts during three year grass-pollen AIT.

Zissler UM, Jakwerth CA, Guerth FM, Pechtold L, Aguilar-Pimentel JA, Dietz K, Suttner K, Piontek G, Haller B, Hajdu Z, Schiemann M, Schmidt-Weber CB, Chaker AM.

EBioMedicine. 2018 Oct

see also press release


The all age asthma cohort (ALLIANCE) - from early beginnings to chronic disease: a longitudinal cohort study.Fuchs O, Bahmer T, Weckmann M, Dittrich AM, Schaub B, Rösler B, Happle C, Brinkmann F, Ricklefs I, König IR, Watz H, Rabe KF, Kopp MV, Hansen G, von Mutius E; ALLIANCE Study Group as part of the German Centre for Lung Research (DZL).

BMC Pulm Med. 2018 Aug


The basophil activation test differentiates between patients with alpha-gal syndrome and asymptomatic alpha-gal sensitization.

Mehlich J, Fischer J, Hilger C, Swiontek K, Morisset M, Codreanu-Morel F, Schiener M, Blank S, Ollert M, Darsow U, Biedermann T, Eberlein B.

J Allergy Clin Immunol. 2018 Aug


Baseline IL-22 expression in patients with atopic dermatitis stratifies tissue responses to fezakinumab.

Brunner PM, Pavel AB, Khattri S, Leonard A, Malik K, Rose S, Jim On S, Vekaria AS, Traidl-Hoffmann C, Singer GK, Baum D, Gilleaudeau P, Sullivan-Whalen M, Fuentes-Duculan J, Li X, Zheng X, Estrada Y, Garcet S, Wen HC, Gonzalez J, Coats I, Cueto I, Neumann AU, Lebwohl MG, Krueger JG, Guttman-Yassky E.

J Allergy Clin Immunol. 2018 Aug


Biomatrix for upper and lower airway biomarkers in patients with allergic asthma.

Zissler UM, Ulrich M, Jakwerth CA, Rothkirch S, Guerth F, Weckmann M, Schiemann M, Haller B, Schmidt-Weber CB, Chaker AM.

J Allergy Clin Immunol. 2018 Aug


The role of environmental factors in allergy: A critical reappraisal.

Gilles S, Akdis C, Lauener R, Schmid-Grendelmeier P, Bieber T, Schäppi G, Traidl-Hoffmann C.

Exp Dermatol. 2018 Nov - Review


Characterization of the honeybee venom proteins C1q-like protein and PVF1 and their allergenic potential.

Russkamp D, Van Vaerenbergh M, Etzold S, Eberlein B, Darsow U, Schiener M, De Smet L, Absmaier M, Biedermann T, Spillner E, Ollert M, Jakob T, Schmidt-Weber CB, de Graaf DC, Blank S.

Toxicon. 2018 Aug


Protective effects of breastfeeding on respiratory symptoms in infants with 17q21 asthma risk variants.

Gorlanova O, Illi S, Toncheva AA, Usemann J, Latzin P, Kabesch M, Dalphin JC, Lauener R, Pekkanen JR, Von Mutius E, Riedler J, Kuehni CE, Röösli M, Frey U; BILD and PASTURE study groups.

Allergy. 2018 Jul


Next generation pollen monitoring and dissemination.

Buters J, Schmidt-Weber C, Oteros J.

Allergy. 2018 Aug


Relations between epidermal barrier dysregulation and staphylococci-dominated microbiome dysbiosis in atopic dermatitis.

 

Altunbulakli C, Reiger M, Neumann AU, Garzorz-Stark N, Fleming M, Huelpuesch C, Castro-Giner F, Eyerich K, Akdis CA, Traidl-Hoffmann C.

J Allergy Clin Immunol. 2018 Jul


Artemisia pollen is the main vector for airborne endotoxin.

 

Oteros J, Bartusel E, Alessandrini F, Núñez A, Moreno DA, Behrendt H, Schmidt-Weber C, Traidl-Hoffmann C, Buters J.

J Allergy Clin Immunol. 2018 Jul

Press release TUM


Context matters: TH2 polarization resulting from pollen composition and not from protein-intrinsic allergenicity.

Aglas L, Gilles S, Bauer R, Huber S, Araujo GR, Mueller G, Scheiblhofer S, Amisi M, Dang HH, Briza P, Bohle B, Horejs-Hoeck J, Traidl-Hoffmann C, Ferreira F.

J Allergy Clin Immunol. 2018 May


Intrauterine smoke exposure deregulates lung function, pulmonary transcriptomes, and in particular insulin-like growth factor (IGF)-1 in a sex-specific manner.

Dehmel S, Nathan P, Bartel S, El-Merhie N, Scherb H, Milger K, John-Schuster G, Yildirim AO, Hylkema M, Irmler M, Beckers J, Schaub B, Eickelberg O, Krauss-Etschmann S.

Sci Rep. 2018 May


Activin-A Is a Pro-Inflammatory Regulator in Type-2-Driven Upper Airway Disease.

Chaker AM, Zissler UM, Poulos N, Wagenmann M, Bas M, Gürth F, Xanthou G, Schmidt-Weber C

Int Arch Allergy Immunol.


A new era for translational atopic dermatitis research and management.

Kabashima K, Biedermann T.

Exp Dermatol.


Induction of IL-10-balanced immune profiles following exposure to LTA from Staphylococcus epidermidis.
Volz T, Kaesler S, Draing C, Hartung T, Röcken M, Skabytska Y, Biedermann T.

Exp Dermatol.


Cutaneous Barriers and Skin Immunity: Differentiating A Connected Network.

Eyerich S, Eyerich K, Traidl-Hoffmann C, Biedermann T.

Trends Immunol. Review.


Type I immune response induces keratinocyte necroptosis and is associated with interface dermatitis.
Lauffer F, Jargosch M, Krause L, Garzorz-Stark N, Franz R, Roenneberg S, Böhner A, Mueller NS, Theis FJ, Schmidt-Weber CB, Biedermann T, Eyerich S, Eyerich K.

J Invest Dermatol.


The use of pharmacogenomics, epigenomics, and transcriptomics to improve childhood asthma management: Where do we stand?

Farzan N, Vijverberg SJ, Kabesch M, Sterk PJ, Maitland-van der Zee AH.

Pediatr Pulmonol.


Polyisocyanopeptide hydrogels: A novel thermo-responsive hydrogel supporting pre-vascularization and the development of organotypic structures.

Zimoch J, Padial JS, Klar AS, Vallmajo-Martin Q, Meuli M, Biedermann T, Wilson CJ, Rowan A, Reichmann E.

Acta Biomater.


Biodiversity: The new kid on the block?

von Mutius E.

J Allergy Clin Immunol.


Early age exposure to moisture damage and systemic inflammation at the age of 6 years.

Karvonen AM, Tischer C, Kirjavainen PV, Roponen M, Hyvärinen A, Illi S, Mustonen K, Pfefferle PI, Renz H, Remes S, Schaub B, von Mutius E, Pekkanen J.

Indoor Air.


Allergic myocardial infarction (Kounis syndrome) after cefuroxime with side-chain cross-reactivity.

Absmaier M, Biedermann T, Brockow K.

J Allergy Clin Immunol Pract. 


Farm dust reduces viral load in human bronchial epithelial cells by increasing barrier function and antiviral responses.

van der Vlugt LEPM, Eger K, Müller C, Ninaber DK, Zarcone MC, Amatngalim GD, Bracher F, von Mutius E, Smits HH, Hiemstra PS.

J Allergy Clin Immunol.


Guideline-compliant prescription of biologicals and possible barriers in dermatological practices in Bavaria.

Schielein MC, Tizek L, Rotter M, Konstantinow A, Biedermann T, Zink A.
J Eur Acad Dermatol Venereol.


Efficacy and safety of fezakinumab (an anti-IL-22 monoclonal antibody) in adults with moderate-to-severe atopic dermatitis inadequately controlled by conventional treatments - A randomized, double-blind, phase 2a trial.

Guttman-Yassky E, Brunner PM, Neumann AU, Khattri S, Pavel AB, Malik K, Singer GK, Baum D, Gilleaudeau P, Sullivan-Whalen M, Rose S, Jim On S, Li X, Guentes-Duculan J, Estrada Y, Garcet S, Traidl-Hoffmann C, Krueger JG, Lebwohl MG.

J Am Acat Dermatol


Expression of inflammasome proteins and inflammasome activation occurs in human, but not in murine keratinocytes.

Sand J, Haertel E, Biedermann T, Contassot E, Reichmann E, French LE, Werner S, Beer HD.

Cell Death Dis.


Asthmatic/wheezing phenotypes in preschool children: Influential factors, health care and urban-rural differences.

Kutzora S, Weber A, Heinze S, Hendrowarsito L, Nennstiel-Ratzel U, von Mutius E, Fuchs N, Herr C; GME Study Group.

Int J Hyg Environ Health.


Asthma and IgE associated polymorphisms affect expression of TH 17 genes.

Worth L, Michel S, Gaertner VD, Kabesch M, Schieck M.

Allergy.


The high molecular weight dipeptidyl peptidase IV Pol d 3 is a major allergen of Polistes dominula venom.

Schiener M, Hilger C, Eberlein B, Pascal M, Kuehn A, Revets D, Planchon S, Pietsch G, Serrano P, Moreno-Aguilar C, de la Roca F, Biedermann T, Darsow U, Schmidt-Weber CB, Ollert M, Blank S.

Sci Rep. 


Recurrent swelling of the ear.

Chylla R, Hein R, Biedermann T, Eyerich K.

J Dtsch Dermatol Ges.


IRF-1 SNPs influence the risk for childhood allergic asthma: A critical role for pro-inflammatory immune regulation.

Landgraf-Rauf K, Boeck A, Siemens D, Klucker E, Vogelsang V, Schmidt S, Kunze S, Weissenbacher C, Graessel A, Schmidt-Weber C, von Mutius E, Schedel M, Schaub B.

Pediatr Allergy Immunol.


After asthma: redefining airways diseases.

Pavord ID, Beasley R, Agusti A, Anderson GP, Bel E, Brusselle G, Cullinan P, Custovic A, Ducharme FM, Fahy JV, Frey U, Gibson P, Heaney LG, Holt PG, Humbert M, Lloyd CM, Marks G, Martinez FD, Sly PD, von Mutius E, Wenzel S, Zar HJ, Bush A.

Lancet.


Successful Treatment of Severe Recalcitrant Hidradenitis Suppurativa with the Interleukin-17A Antibody Secukinumab.

Schuch A, Fischer T, Boehner A, Biedermann T, Volz T.

Acta Derm Venereol.