Cluster Allergy and Immunity - Nasal polyp, immunohistology (J. Esser-von Bieren)

Cluster Allergy and Immunity

Nasal polyp, immunohistology (J. Esser-von Bieren)

Cluster Allergy and Immunity - REM Ambrosia psilostachya (C. Weil, I. Weichenmeier, J. Buters)

Cluster Allergy and Immunity

REM Ambrosia psilostachya (C. Weil, I. Weichenmeier, J. Buters)

Cluster Allergy and Immunity - Gut cross section, histological staining (C. Ohnmacht)

Cluster Allergy and Immunity

Gut cross section, histological staining (C. Ohnmacht)

Research for a future without allergies

The Cluster Allergy and Immunity CAI integrates institutes with congruent research activities aiming at allergy prevention and remission. CAI partners include the Helmholtz Center Munich, the TUM, LMU, UNIKA-T Augsburg and the University Hospital Regensburg that practice research in a tightly integrated way and share a translational and interdisciplinary spirit that fosters creativity and innovation.​ Insights from the interplay of environment and men as well as cellular mechanisms are deliberately directed into preclinical models and - if proven effective - into clinical practice.

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News

SAVE THE DATE

CAI Seminar by Prof. Murray "Immunoregulation by amino acid metabolism”

October 19th 2pm at the ZAUM

 


Coming next

CAI Seminar by Frederic de Blay November 22nd


 

left to right: Dr. Matthias Reiger, Augsburg; Jana Mehlich, München; PD Dr. Patrick M. Brunner, MSc, Wien; Prof. Thomas Werfel DGAKI; Dr. Jose Oteros, München; PD Dr. Daniel Piotr Potaczek, Marburg
Picture by DGAKI-2018

Congratulations:

Dr. Matthias Reiger, UNIKA-T Augsburg and Jana Mehlich, Klinik und Poliklinik für Dermatologie und Allergologie, TU Munich reseived the "Nachwuchsförderpreis" sponsored by the Siemens Healthcare Diagnostics GmbH, Eschborn and Dr. Jose Oteros from the ZAUM - "Zentrum für Allergie und Umwelt" received the "Förderpreis - specific immunotherapy“ by the Allergopharma GmbH & Co. KG, Reinbek.

They were awarded within the annual meeting 2018 of the "deutsche Gesellschaft für Allergologie und klinische Immunologie (DGAKI)" in Dresden.

 


 

von links: Dr. Alexander Zink (Oberarzt/ Dermatologie), Teilnehmerin mit dem jüngsten Teilnehmer, PD Dr. Kuschel (Leiterin der Geburtshilfe und Perinatalmedizin) und Prof. Biedermann (Klinikdirektor der Dermatologie).

Die "Munich Atopy Prediction Study" (MAPS) untersucht Risikofaktoren für Neurodermitis bei Kindern. Hierfür rekrutiert die Klinik für Dermatologie und Allergologie insgesamt 300 schwangere Frauen, deren Kinder im Klinikum rechts der Isar zur Welt kommen und im Großraum München wohnen werden. Teilnehmende Kinder werden eng betreut und erhalten im Fall einer Erkrankung an Neurodermitis die bestmögliche Therapie durch die Ärzte der Dermatologischen Universitätsklinik am Klinikum rechts der Isar.

Neurodermitis ist eine Volkskrankheit, von der zehn bis 15 Prozent der Kinder und zwei bis drei Prozent der Erwachsenen betroffen sind – mit jährlich steigender Tendenz. Die medizinische Forschung arbeitet daran, ein besseres Verständnis für das Erkrankungsbild zu gewinnen, um bessere Therapien entwickeln zu können. Wir fragen uns, welche Faktoren das Entstehen der Krankheit beeinflussen? Welche Rolle spielen Hautbakterien, die Darmflora, die Umwelt, unsere Gene? In der MAPS-Studie suchen wir ganz gezielt nach diesen Risikofaktoren für die Entwicklung allergologischer und dermatologischer Erkrankungen.


 

Atopic dermatitis: staphylococci-dominated microbiome influence skin barrier function

Staphylococcus aureus is the dominat skin associated bacterium in atopic dermatis. A recently published Paper of CAI Researchers in cooperation with researchers from Zurich could show that this microbiome dysbiosis influence also the skin barrier function.

 

Publication

Relations between epidermal barrier dysregulation and staphylococci-dominated microbiome dysbiosis in atopic dermatitis.

Altunbulakli C, Reiger M, Neumann AU, Garzorz-Stark N, Fleming M, Huelpuesch C, Castro-Giner F, Eyerich K, Akdis CA, Traidl-Hoffmann C.

J Allergy Clin Immunol. 2018 Jul

Press release TUM, August 10, 2018 (in german language)


 

Sucsessful EAACI congress for CAI Members - Congratulation to all 9 Poster Prize Winners

Klick for more information


 

Congratulation to Kilian Eyerich for the german "Psoriasis Preis"

Prof. Dr. med. Kilian Eyerich, PhD was honored with the "Deutscher Psoriasis‐Preis" in the context of the „DDG kompakt und praxisnah“  meeting of the German Society for Dermatology (DDG) in Stuttgart. The DDG appreciate Kilian Eyerich’s research success in the interaction of the immune system with chronic skin inflammation. The price (in the amount of 30,000€) will finance his further research projects in the field.

Press release (in german)


 

Appointment for Francesca Alessandrini

We would like to congratulate Dr. Francesca Alessandrini on her appointment as an extraordinary professor for "experimental allergology". She is als Head of the ZAUM research Group.

Link to her research


 

Ernennung

Wir gratulieren Frau Dr. Francesca Alessandrini ganz herzlich zu ihrer Ernennung zur außerplanmäßigen Professorin der TUM für das Fachgebiet Experimentelle Allergologie. Sie ist Arbeitsgruppenleiterin am Zentrum für Allergie und Umwelt.

zu Ihrer Arbeitsgruppe


CAI Publications

 

Next generation pollen monitoring and dissemination.

Buters J, Schmidt-Weber C, Oteros J.

Allergy. 2018 Aug


Characterization of the honeybee venom proteins C1q-like protein and PVF1 and their allergenic potential.

Russkamp D, Van Vaerenbergh M, Etzold S, Eberlein B, Darsow U, Schiener M, De Smet L, Absmaier M, Biedermann T, Spillner E, Ollert M, Jakob T, Schmidt-Weber CB, de Graaf DC, Blank S.

Toxicon. 2018 Aug


Protective effects of breastfeeding on respiratory symptoms in infants with 17q21 asthma risk variants.

Gorlanova O, Illi S, Toncheva AA, Usemann J, Latzin P, Kabesch M, Dalphin JC, Lauener R, Pekkanen JR, Von Mutius E, Riedler J, Kuehni CE, Röösli M, Frey U; BILD and PASTURE study groups.

Allergy. 2018 Jul


Relations between epidermal barrier dysregulation and staphylococci-dominated microbiome dysbiosis in atopic dermatitis.

 

Altunbulakli C, Reiger M, Neumann AU, Garzorz-Stark N, Fleming M, Huelpuesch C, Castro-Giner F, Eyerich K, Akdis CA, Traidl-Hoffmann C.

J Allergy Clin Immunol. 2018 Jul



Artemisia pollen is the main vector for airborne endotoxin.

Oteros J, Bartusel E, Alessandrini F, Núñez A, Moreno DA, Behrendt H, Schmidt-Weber C, Traidl-Hoffmann C, Buters J.

J Allergy Clin Immunol. 2018 Jul


Context matters: TH2 polarization resulting from pollen composition and not from protein-intrinsic allergenicity.

Aglas L, Gilles S, Bauer R, Huber S, Araujo GR, Mueller G, Scheiblhofer S, Amisi M, Dang HH, Briza P, Bohle B, Horejs-Hoeck J, Traidl-Hoffmann C, Ferreira F.

J Allergy Clin Immunol. 2018 May


Intrauterine smoke exposure deregulates lung function, pulmonary transcriptomes, and in particular insulin-like growth factor (IGF)-1 in a sex-specific manner.

Dehmel S, Nathan P, Bartel S, El-Merhie N, Scherb H, Milger K, John-Schuster G, Yildirim AO, Hylkema M, Irmler M, Beckers J, Schaub B, Eickelberg O, Krauss-Etschmann S.

Sci Rep. 2018 May


Activin-A Is a Pro-Inflammatory Regulator in Type-2-Driven Upper Airway Disease.

Chaker AM, Zissler UM, Poulos N, Wagenmann M, Bas M, Gürth F, Xanthou G, Schmidt-Weber C

Int Arch Allergy Immunol. 2018


Cutaneous Barriers and Skin Immunity: Differentiating A Connected Network.


Eyerich S, Eyerich K, Traidl-Hoffmann C, Biedermann T.

2018, Trends Immunol. - Review.


Type I immune response induces keratinocyte necroptosis and is associated with interface dermatitis.


Lauffer F, Jargosch M, Krause L, Garzorz-Stark N, Franz R, Roenneberg S, Böhner A, Mueller NS, Theis FJ, Schmidt-Weber CB, Biedermann T, Eyerich S, Eyerich K.

2018, J Invest Dermatol.


The use of pharmacogenomics, epigenomics, and transcriptomics to improve childhood asthma management: Where do we stand?


Farzan N, Vijverberg SJ, Kabesch M, Sterk PJ, Maitland-van der Zee AH.

2018, Pediatr Pulmonol.


Exposure to non-microbial N -Glycolylneuraminic acid protects farmers’ children against airway inflammation and colitis.

Remo Frei, Ruth Ferstl, Caroline Roduit, Mario Ziegler Dipl-Ing, Elisa Schiavi, Weronika Barcik, Noelia Rodriguez-Perez, Oliver F. Wirz, Marcin Wawrzyniak, Benoit Pugin, Dirk Nehrbass, Marek Jutel, Sylwia Smolinska, Patrycja Konieczna, Christian Bieli, Susanne Loeliger, Marco Waser, Göran Pershagen, Josef Riedler, Martin Depner, Bianca Schaub, Jon Genuneit, Harald Renz, Juha Pekkanen, Anne M. Karvonen, Jean-Charles Dalphin, Marianne van Hage, Gert Doekes, Mübeccel Akdis, Charlotte Braun-Fahrländer, Cezmi A. Akdis, Erika von Mutius, Liam O’Mahony, Roger P. Lauener.

2017, J Allergy Clin Immun.

Press release


 

Cabinet approves the electronic pollen information network "ePIN"

Prof. Dr. Jeroen Buters, ZAUM 

ePIN-network map     press release

 

 

 

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